ISSN (Online): 2321-3418
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Medical Sciences and Pharmacy
Open Access

Review Article -Antibiotics Resistant to Different Microorganisms

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DOI: 10.18535/ijsrm/v10i12.mp04· Pages: 768-780· Vol. 10, No. 12, (2022)· Published: December 29, 2022
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Abstract

Over a years, people mostly who were struggled with primary cause of infection and diseases by microorganisms, and utmost care has been taken that some antibiotics are highly resistant to bac- terial species and emergence of broad-range of antibiotic therapy. Broad-spectrum antibiotics have widely emerged in various ways to kill microorganisms that tend to cause illness and diseases in the human era. New resistance mechanisms are emerging and spreading worldwide. However, some bacteria may become resistant to commonly used antibiotics. Antibiotic-resistant bacteria are bacteria that are inhibited or killed by antibiotics as they can able to survive and even rapidly spread by multiplying in the human system in the presence of antibiotics. The major mechanisms interrupted in bacterial resistance are limitation of drug uptake, modification of a drug target, in- activation of a drug, and active efflux of a drug. Those bacteria are resistant to many antibiotics and they are termed Multi-resistant organisms. For example, benzylpenicillin has very little effect on most organisms in the human digestive system. Staphylococcus aureus and Neisseria gonor- rhoeae are resistant to benzylpenicillin, Methicillin-resistant Staphylococcus aureus, Vancomycin- resistant Enterococcus, Multi-drug-resistant Mycobacterium tuberculosis, Carbapenem-resistant Enterobacteriaceae. Different methods were used for detecting the antibiotic resistance to different microorganisms mainly Gram-negative bacilli, and Gram-positive bacteria. The common ways that antibiotic-resistant bacteria can be transmission in hospitals from person to person is through contact with contaminated hands of hospital staff, door handles, hospital beds, and equipment. Important ways can be followed to prevent antibiotic resistance by minimizing unnecessary over- prescribing of antibiotics by medical practitioners and maintaining proper hygiene such as hand washing by use of regular infection control.

Keywords

Antibiotic resistance organismsEnterobacteriaceaeAntibiotics groupTesting antibiotic resistance to different organisms

References

  1. https://www.who.int/news-room/fact-sheets/detail/antibiotic-resistance 2018Google Scholar ↗
  2. https://www.who.int/news-room/fact-sheets/detail/antibiotic-resistance 17 Nov 2021Google Scholar ↗
  3. Cesur, Salih -.Demiroz, Ali, (2013)-The Mechanisms of Resistance to Antibiotics,Google Scholar ↗
  4. Medical journal of Islamic world Academy of Sciences 21.4,138-142,//dx.doi.org/Google Scholar ↗
  5. https://www.journalagent.com/ias/pdfs/IAS_21_4_138_142.pdfGoogle Scholar ↗
  6. Yohei Doi, Jun-ichi Wachino, Yoshichika Arakawa, 2016 The Emergence of Acquired 16S Ribosomal RNA Methyltransferases, Published on Infect Dis Clin North Am. 2016 Jun; 30(2): 523–537. DOI: 10.1016/j.idc.2016.02.011 PMC4878400DOI ↗Google Scholar ↗
  7. Nikaido H, Thanassi DG. 1993. Penetration of lipophilic agents with multiple protonation sites into bacterial cells: Tetracyclines and fluoroquinolones as examples. Antimicrob Agents Chemother 37: 1393–1399.Google Scholar ↗
  8. Mortimer PG, Piddock LJ. 1993. The accumulation of five antibacterial agents in porin-de- ficient mutants of Escherichia coli. J Antimicrob Chemother 32: 195–213Google Scholar ↗
  9. Trudy H.Grossman, 2016 Apr; 6(4):a025387.Tetracycline Antibiotics and Resistance, doi:10.1101/cshperspect.a025387,https://www.ncbi.nlm.nih.gov/pmc/arti- cles/PMC4817740/DOI ↗Google Scholar ↗
  10. Jones et al. 2014, Reference Module in Biomedical Sciences, 2021,https://www.sciencedi- rect.com/topics/medicine-and-dentistry/tetracycline-resistanceGoogle Scholar ↗
  11. Speer BS, Bedzyk L, Salyers AA. 1991. Evidence that a novel tetracycline resistance gene found on two Bacteroides transposons encodes an NADP-requiring oxidoreductase.Google Scholar ↗
  12. J Bacteriol 173: 176–183. [PMC free article] [PubMed] [Google Scholar]Google Scholar ↗
  13. J C Pechere, Int J Antimicrob Agents, 2001; 18 Suppl 1: S25-8. Macrolide resistance mech- anisms in Gram-positive cocci, PMID: 11574191, DOI 10.1016/s0924-8579(01)00407-1DOI ↗Google Scholar ↗
  14. Matsuoka M, Yakugaku Zasshi 2000, Apr; Study of macrolide, lincosamide, and strepto- gramin B antibiotics resistance in Staphylococcus aureus, 120(4): 374-86. PMID: 1077425 DOI: 10.1248/yakushi1947.120.4_374DOI ↗Google Scholar ↗
  15. Courvalin P, Ounissi H, Arthur M, Antimicrob Chemother, 1985 Jul;16 Suppl A: 91-100, Multiplicity of macrolide-lincosamide-Streptogramin antibiotic resistance determinants, PMID: 3932312, DOI: 10.1093/Jan/16.suppl_a.91DOI ↗Google Scholar ↗
  16. https://www.researchgate.net/figure/Antibiotic-resistance-dissemination-mechanisms-and- pathways-A-Schematic-overview-of_fig1_340266119Google Scholar ↗
  17. Murray I.A. Shaw W.V.(1997) O-acetyltransferases for chloramphenicol and other natural products. Antimicrob. Agents Chemother41, 1-6Google Scholar ↗
  18. Matilde Fernandez, Susana conde, Jesus de la Torre, Carlos Molina-Santiago, 2012 Feb; 56(2): 1001–1009. Mechanisms of resistance to Chloramphenicol in Pseudomonas putida KT2440 doi: 10.1128/AAC.05398-11DOI ↗Google Scholar ↗
  19. Stefan Schwarz, Nov 2004, Molecular basis of bacterial resistance to chloramphenicol FEMS Microbiology Reviews, Volume 28, Issue 5, November 2004, Pages 519– 542, https://doi.org/10.1016/j.femsre.2004.04.001DOI ↗Google Scholar ↗
  20. George A. Jacoby, 2005, Mechanisms of resistance to Quinolones, Clinical Infectious Dis- eases, Volume 41, Issue Supplement_2, July 2005, Pages S120–S126, https://doi.org/10.1086/428052DOI ↗Google Scholar ↗
  21. Jason H Malenfant, 2021, Rifampicin mono-resistant Tuberculosis - A review of an un- common but growing challenge for global tuberculosis control, Open Forum Infectious Diseases, Volume 8, Issue 2, February 2021, ofab018, https://doi.org/10.1093/ofid/ofab018DOI ↗Google Scholar ↗
  22. Yu pang, 2013, Study of the Rifampicin monoresistance mechanism in Mycobacterium tu- berculosis, DOI:https://doi.org/10.1128/AAC.01024-12DOI ↗Google Scholar ↗
  23. Ola skold, 2000, Sulfonamide resistance: mechanisms and trends, Jun 2000, 155-160, https://doi.org/10.1054/drup.2000.0146DOI ↗Google Scholar ↗
  24. George M.Eliopoulos, 2001, Resistance to Trimethoprim – Sulfamethoxazole, Jun 2001, 1608-1614, https://doi.org/10.1086/320532DOI ↗Google Scholar ↗
  25. Skold, 2001, Resistance to trimethoprim and sulfonamides, May-Aug 2001;32(3-4):261- 73. DOI: 10.1051/vetres:2001123DOI ↗Google Scholar ↗
  26. Francois lebreton, Vincent Cattoir, Resistance to glycopeptide, Mar 2019, https://doi.org/10.1002/9781119593522.ch3DOI ↗Google Scholar ↗
  27. P.Courvallin, Institut Pasteur, Paris, France, Glycopepetide resistance, Mar 1999, https://doi.org/10.1111/j.1469-0691.1999.tb00756.xDOI ↗Google Scholar ↗
  28. L.Barth Reller, Melvin Weinstein, James H.Jorgensen, Dec 2009, Antimicrobial susceptibility test- ing, A Review of General principles and Contemporary practices. https://doi.org/10.1086/647952DOI ↗Google Scholar ↗
  29. M. Benkova, O. Soukup, J. Marek, May 2020, Antimicrobial susceptibility testing: currently used methods and devices and the near future in clinical practice. https://doi.org/10.1111/jam.14704DOI ↗Google Scholar ↗
  30. Ad C.Fluit, Maarten R. Visser, Franz-Josef Schmitz, Oct 2001, Molecular detection of Antimicro- bial Resistance, https://doi. org/10.1128/CMR.14.4.836-871.2001DOI ↗Google Scholar ↗
  31. https://www.nfid.org/antibiotic-resistance/how-to-prevent-antibiotic-resistance/Nov 2020Google Scholar ↗
  32. https://www.cdc.gov/drugresistance/us-activities.html, Nov 2021,Google Scholar ↗
  33. Dr.Beth Bell, Sep 2016, CDC, Prevention and Control of Antibiotic Resistance: The Public Health Approach, https://www.hhs.gov/sites/default/files/bell.pdfGoogle Scholar ↗
Author details
Sindhu B
Ramachandra university.
✉ Corresponding Author
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krishna L
Kakathiya university
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Mahesh Chandra. N
Kakathiya University
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