A 5-Year Retrospective Study of Microbial Isolates and Antibiogram from Endocervical Swabs of Infertile Women Attending Gynaecological Clinic At Bingham University Teaching Hospital Jos, Nigeria
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Background: Infertility is a major public health concern with serious social and emotional burden. Genital tract infections contribute significantly to infertility by causing pelvic inflammatory disease which later results in tubal damage. This study aimed to determine the commonly isolated microorganisms from endocervical swab cultures of women with infertility and the antibogram sensitivity..
Methodology: All records of microbial culture and antibiotic sensitivity test results of endocervical swabs of infertile women attending the gynaecological clinic at the Bingham University Teaching Hospital, Jos from 1st January 2019 to 31st December, 2024 were retrieved and entered into excel sheet, cleaned and exported into the IBM SPSS Statistics version 25.0 and analyzed. Descriptive analysis was done for all relevant variables and presented in tables and chi-square was used to test for degree of association and P<0.05 was taken as statistically significant.
Result: Of the four hundred endocervical swab results retrieved, 121(30.3%) had normal cells with positivity index of 279(69.8%) on microscopy. There are six microbial organisms isolated with Staphylococcus aureus as the most commonly isolated in 41.3% (165/400), followed by Klebsiella spp 19%(76/400). Gentamycin and Ofloxacin were the only antibiotics with a >40% sensitivity rates.
Conclusion: The most prevalent microorganisms in the endocervix of infertile women in our facility were Staphylococcus aureus and Klebsiella spp while Psudomonas is the least prevalent. These organisms are mostly sensitive to Gentamycin, Ofloxacin and Levofloxacin. Empirical treatment with these antibiotics in the presence of genital tract infections may help to reduce the risk of infertility from tubal damage.
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Copyright (c) 2025 Lucky Changkat Lohnan, Dr. James Bitrus, Dr. Oluwaseye F. Oyeniran, Dr, Adikpe E. Edugbe, Caleb E. Odonye, Dr. Zaman N. Joshua
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