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Spirituality Intervention Impact on Spiritual Well-Being, Quality of Life, Sleep Quality, Anxiety, Distress and Suffering In Women With Cancer:Systematic Review and Meta-Analysis

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DOI: 10.18535/ijsrm/v14i01.mp05· Pages: 2432-2454· Vol. 14, No. 01, (2026)· Published: January 17, 2026
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Abstract

Introduction: The burden of cancer in women has a physical and emotional impact on health. It needed an intervention that responded to the situation. The purpose of this study was to look into how spiritual interventions affected the spiritual well-being, quality of life, sleep, anxiety, distress, and suffering of women with cancer. Method: A systematic review and meta-analysis were conducted in this study. The articles were searched from six databases including Elicit, Europe PMC, PubMed, Sage Knowledge, and Wiley between 2018 and 2023. The Jadad scale was employed for article quality assessment. Report writing follows the PRISMA 2020 checklist. Results: Thirteen higher-quality articles were included in the review. Spiritual intervention relative to control was associated with an improvement in spiritual well-being, SMD = 2.00 (95% CI: 0,93-3.07), p < 0,0003, I2 = 97%, p <0.00001, quality of life functional scale, SMD = 0.69 (-0.01-1.39), p = 0.05, I2 = 94%, p <0.00001, quality of life six single-item scales, WMD = -5.69 (-9.32 to -2.05), p = 0.002, I2 = 0%, p = 0.84, and anxiety, distress, and suffering, SMD = -0.82 (-1.37 to -0.27), p = 0.003, I2 = 83%, p < 0,0001. It was not associated with an improvement in quality of life symptoms scales, sleep quality (PSQI), and sleep quality (actigraphy). Conclusions: Spiritual intervention was effective in improving spiritual well-being, anxiety, distress and suffering, and the quality of life functional scale. It had no impact on raising the quality of life symptoms ratings and had no discernible influence on sleep quality.

Keywords

Anxietycancerquality of lifesleep qualityspiritual interventionspiritual well-being

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Author details
Siti Mulidah
Islamic University of Prof. K.H. Saifuddin Zuhri Purwokerto
✉ Corresponding Author
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Dwi Sarwani Sri Rejeki
Department of Public Health, Faculty of Health Sciences, Universitas Jenderal Soedirman Purwokerto
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Hartono Hartono
Islamic University of Prof. K.H. Saifuddin Zuhri Purwokerto
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Asrin Asrin
Ministry of Health Health Polytechnic Semarang
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Asiandi Asiandi
Faculty of Health Sciences, Muhammadiyah University of Purwokerto
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